ea0049gp26 | Adrenal 3 | ECE2017
Meireles Cinthia
, Neves Francisco
, Simeoni Luiz
, Lofrano-Porto Adriana
Background: Pheochromocytomas (PHEO) are rare neuroendocrine tumors derived from chromaffin cells of the adrenal medulla. CatecholaminsÂ’ secretion is associated with a high risk of cardiovascular complications. Malignancy is rare, but still demands effective treatment. Metformin has been shown to have antiproliferative properties in several cancer cell lines, possibly related to its ability to inhibit cell proliferation pathways. Accordingly, we aimed to evaluate the effe...